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首页-小分子抑制剂&激动剂-Others-Other Targets-Ionomycin
Ionomycin

Chemical Structure : Ionomycin

CAS No.: 56092-81-0

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Ionomycin (SQ23377)

货号: PC-62654Not For Human Use, Lab Use Only.

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes.

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10 mg ￥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes.
Ionomycin also used to stimulate the intracellular production of the following cytokines; interferon, perforin, IL-2, and IL-4 - usually in conjunction with PMA.

物理化学性质&存储条件

分子量 709
分子式 C41H72O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2a[2'S*,5'R*(S*)],5b(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-

参考文献

1. Gibbons E, et al. Biochim Biophys Acta. 2014 Oct;1838(10):2607-14.

2. Wang Y, et al. Ann Hematol. 2014 May;93(5):735-46.

3. Han S, et al. PLoS One. 2013 Oct 9;8(10):e76717.

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