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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-Inupadenant
Inupadenant

Chemical Structure : Inupadenant

CAS No.: 2246607-08-7

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Inupadenant (EOS-850, EOS100850)

货号: PC-38365Not For Human Use, Lab Use Only.

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

    物理化学性质&存储条件

    分子量 604.652
    分子式 C25H26F2N8O4S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazin-1-yl)ethyl)-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

    参考文献

    1. Laurence Buisseret, et al. Journal of Clinical Oncology, Volume 39, Issue 15_suppl.

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