Inupadenant (EOS-850, EOS100850)

Chemical Structure : Inupadenant

CAS No.: 2246607-08-7

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货号: PC-38365Not For Human Use, Lab Use Only.

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

规格	价格	库存
2 mg	￥2580	In stock
5 mg	￥3980	In stock
10 mg	￥5980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

物理化学性质&存储条件

分子量	604.652
分子式	C25H26F2N8O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazin-1-yl)ethyl)-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

参考文献

1. Laurence Buisseret, et al. Journal of Clinical Oncology, Volume 39, Issue 15_suppl.