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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Aryl hydrocarbon Receptor (AhR)-Indirubin
Indirubin

Chemical Structure : Indirubin

CAS No.: 479-41-4

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Indirubin (Couroupitine B, Indigo red)

货号: PC-23914Not For Human Use, Lab Use Only.

Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM.

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10 mg ￥580 In stock
25 mg ￥880 In stock
50 mg ￥1280 In stock
100 mg ￥1980 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM.

物理化学性质&存储条件

分子量 262.27
分子式 C16H10N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

[2,3'-Biindolinylidene]-2',3-dione

参考文献

1. Diao X, et al. Nat Commun. 2025 Feb 3;16(1):1282.

2. Kim MH, et al. J Ethnopharmacol. 2013 Jan 9;145(1):214-9.

3. Hsieh WL, et al. J Dermatol Sci. 2012 Aug;67(2):140-6.

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