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Imisopasem manganese

Chemical Structure : Imisopasem manganese

CAS No.: 218791-21-0

Imisopasem manganese (M-40403;GC-4419)

货号: PC-43504Not For Human Use, Lab Use Only.

A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.

规格 价格 库存 数量
5 mg ¥1200 In stock
10 mg ¥1920 In stock
25 mg ¥3600 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen; significantly mitigates the increased sensitivity of old fibroblasts to ionizing radiation and chemotherapy and partially restores mitochondrial function without affecting ionizing radiation or chemotherapy-induced cancer cell killing.

Chemotherapeutic Agents

Phase 2 Clinical

物理化学性质&存储条件

分子量 479.348385
分子式 C21H31Cl2MnN5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: 16 mg/mL (Need ultrasonic and warming)

Chemical Name/SMILES

Manganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7H-dibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]-, (PB-7-11-2344'3')-

参考文献

1. Tuder RM, et al. Am J Respir Cell Mol Biol. 2003 Jul;29(1):88-97.

2. Mapuskar KA, et al. Cancer Res. 2017 Aug 1. pii: canres.0106.2017.

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