Chemical Structure : Imisopasem manganese
CAS No.: 218791-21-0
货号: PC-43504Not For Human Use, Lab Use Only.
A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1200 | In stock | |
10 mg | ¥1920 | In stock | |
25 mg | ¥3600 | In stock | |
50 mg | Get quote |
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A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen; significantly mitigates the increased sensitivity of old fibroblasts to ionizing radiation and chemotherapy and partially restores mitochondrial function without affecting ionizing radiation or chemotherapy-induced cancer cell killing.
Chemotherapeutic Agents
Phase 2 Clinical
分子量 | 479.348385 | |
分子式 | C21H31Cl2MnN5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
H2O: 16 mg/mL (Need ultrasonic and warming) |
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Chemical Name/SMILES |
Manganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7H-dibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]-, (PB-7-11-2344'3')- |
1. Tuder RM, et al. Am J Respir Cell Mol Biol. 2003 Jul;29(1):88-97.
2. Mapuskar KA, et al. Cancer Res. 2017 Aug 1. pii: canres.0106.2017.
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