Iloperidone |CAS:133454-47-4 Probechem Biochemicals

Chemical Structure : Iloperidone

CAS No.: 133454-47-4

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Iloperidone (HP-873)

货号: PC-45232Not For Human Use, Lab Use Only.

Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors.

规格	价格	库存
50 mg	￥780	In stock
100 mg	￥1280	In stock
250 mg	￥1980	In stock
1 g		Get quote

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生物&药学活性

Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors.
Iloperidone (HP-873) is used for the treatment of schizophrenia.

物理化学性质&存储条件

分子量	426.4806
分子式	C24H27FN2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-

参考文献

1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.

2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.

3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.

Iloperidone (HP-873)

生物&药学活性

物理化学性质&存储条件

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Iloperidone (HP-873)

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