Ilaprazole |CAS:172152-36-2 Probechem Biochemicals

Chemical Structure : Ilaprazole

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Ilaprazole (IY81149;IY-81149;IY 81149)

货号: PC-42413Not For Human Use, Lab Use Only.

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.

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生物&药学活性

A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM; dose-dependently increases gastric pH in anesthetized rats, exhibits superior potency against gastric acid secretion compared with omeprazole.

Ulcer

Approved

物理化学性质&存储条件

分子量	366.43682
分子式	C19H18N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 35 mg/mL
Chemical Name/SMILES	1H-Benzimidazole, 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-

参考文献

1. Kim EJ, et al. Arzneimittelforschung. 2001 Jan;51(1):51-9.

2. Kwon D, et al. Arzneimittelforschung. 2001;51(3):204-13.

3. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.

Ilaprazole (IY81149;IY-81149;IY 81149)

生物&药学活性

物理化学性质&存储条件

参考文献

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Ilaprazole (IY81149;IY-81149;IY 81149)

生物&药学活性

物理化学性质&存储条件

参考文献

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