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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Iclaprim
Iclaprim

Chemical Structure : Iclaprim

CAS No.: 192314-93-5

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Iclaprim (AR-100)

货号: PC-23224Not For Human Use, Lab Use Only.

Iclaprim (AR-100) is a selective dihydrofolate reductase (DHFR) inhibitor, is active against methicillin, TMP and vancomycin resistant strains, has MIC90 of 0.5 ug/mL against C. trachomatis and C. pneumoniae.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Iclaprim (AR-100) is a selective dihydrofolate reductase (DHFR) inhibitor, is active against methicillin, TMP and vancomycin resistant strains, has MIC90 of 0.5 ug/mL against C. trachomatis and C. pneumoniae.

物理化学性质&存储条件

分子量 354.41
分子式 C19H22N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-((2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl)pyrimidine-2,4-diamine

参考文献

1. Kohlhoff SA, et al. Antimicrob Agents Chemother. 2004 May;48(5):1885-6.

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