Ibrutinib-biotin |CAS:1599432-18-4 Probechem Biochemicals

Chemical Structure : Ibrutinib-biotin

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Ibrutinib-biotin (Ibrutinib biotin)

货号: PC-42104Not For Human Use, Lab Use Only.

Ibrutinib-biotin is a chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase.

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生物&药学活性

Ibrutinib-biotin is a chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase.
Ibrutinib-biotin extracted from patent WO2014059368A1 Compound 1-5.

物理化学性质&存储条件

分子量	1097.374
分子式	C56H80N12O9S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-4-oxo-2-buten-1-yl]methylamino]butyl]-N5-[19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-

参考文献

1. Betty Y. CHANG, et al. Companion diagnostics for tec family kinase inhibitor therapy. WO 2014059368 A1.

Ibrutinib-biotin (Ibrutinib biotin)

生物&药学活性

物理化学性质&存储条件

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Ibrutinib-biotin (Ibrutinib biotin)

生物&药学活性

物理化学性质&存储条件

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