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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Integrin-IVL745
IVL745

Chemical Structure : IVL745

CAS No.: 229627-58-1

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IVL745 (IVL-745)

货号: PC-49345Not For Human Use, Lab Use Only.

IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

    物理化学性质&存储条件

    分子量 592.649
    分子式 C31H36N4O8
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(N-(3,4-dimethoxybenzyl)-2-(2-(3-methoxy-4-(3-(o-tolyl)ureido)phenyl)acetamido)acetamido)propanoic acid

    参考文献

    1. Norris V, et al. J Allergy Clin Immunol. 2005 Oct;116(4):761-7.

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