ITX-5061 hydrochloride |CAS:1252679-52-9 Probechem Biochemicals

Chemical Structure : ITX-5061 hydrochloride

CAS No.: 1252679-52-9

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ITX-5061 hydrochloride (ITX5061)

货号: PC-62103Not For Human Use, Lab Use Only.

ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels.

规格	价格	库存
5 mg	￥2780	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels.
ITX-5061 inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice.
ITX-5061 inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication.

物理化学性质&存储条件

分子量	620.158
分子式	C30H38ClN3O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide hydrochloride

参考文献

1. Masson D, et al. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2054-60.

2. Zhu H, et al. J Infect Dis. 2012 Feb 15;205(4):656-62.

3. Syder AJ, et al. J Hepatol. 2011 Jan;54(1):48-55.

ITX-5061 hydrochloride (ITX5061)

生物&药学活性

物理化学性质&存储条件

参考文献

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ITX-5061 hydrochloride (ITX5061)

生物&药学活性

物理化学性质&存储条件

参考文献

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