Chemical Structure : ISS610
货号: PC-26446Not For Human Use, Lab Use Only.
ISS610 (ISS-610) is a selective peptidomimetic inhibitor of STAT3 dimerization with IC50 of 42 uM for STAT-DNA binding disruption, interacts with SH2 domain of STAT3 and shows 7.4-fold selective over STAT1.
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ISS610 (ISS-610) is a selective peptidomimetic inhibitor of STAT3 dimerization with IC50 of 42 uM for STAT-DNA binding disruption, interacts with SH2 domain of STAT3 and shows 7.4-fold selective over STAT1.
| 分子量 | 503.45 | |
| 分子式 | C23H26N3O8P | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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1. Shahani VM, et al. Bioorg Med Chem. 2011 Mar 1;19(5):1823-38.
2. Gunning PT, et al. Bioorg. Med. Chem. Lett. 2007;17:1875.
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