ISO-66 |CAS:1819996-72-9 Probechem Biochemicals

Chemical Structure : ISO-66

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ISO-66 (ISO66)

货号: PC-63118Not For Human Use, Lab Use Only.

ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM.

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生物&药学活性

ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM.
ISO-66 enhances specific and non-specific anticancer immune responses, decreases tumor burden in melanoma or colon cancer mice.
ISO-66 is an analog of ISO-1 with improved characteristics.

物理化学性质&存储条件

分子量	237.23
分子式	C12H12FNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanone,1-[3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-5-isoxazolyl]

参考文献

1. Ioannou K, et al. Int J Oncol. 2014 Oct;45(4):1457-68.

ISO-66 (ISO66)

生物&药学活性

物理化学性质&存储条件

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ISO-66 (ISO66)

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