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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-ISM061-022
ISM061-022

Chemical Structure : ISM061-022

CAS No.:

ISM061-022

货号: PC-23931Not For Human Use, Lab Use Only.

ISM061-018-2 is a potential pan-Ras inhibitor with IC50 values in the micromolar range, shows selectivity toward certain KRAS mutants.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ISM061-018-2 is a potential pan-Ras inhibitor with IC50 values in the micromolar range, shows selectivity toward certain KRAS mutants.

物理化学性质&存储条件

分子量 344.42
分子式 C21H20N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(2-methoxy-3-methylphenyl)pyrimidin-4-yl)-1-methyl-1H-indol-4-amine

参考文献

1. Ghazi Vakili M, et al. Nat Biotechnol. 2025 Jan 22. doi: 10.1038/s41587-024-02526-3.

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