IRAP-IN-1 | IRAP inhibitor | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aminopeptidase-IRAP-IN-1

Chemical Structure : IRAP-IN-1

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IRAP-IN-1 (IRAP inhibitor)

货号: PC-72273Not For Human Use, Lab Use Only.

IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.

规格	价格	库存	数量
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100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.
IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy.

物理化学性质&存储条件

分子量	597.696
分子式	C35H40N3O4P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((S)-2-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-4,4-diphenylbutyl)((R)-1-amino-3-phenylpropyl)phosphinic acid

参考文献

1. Paraskevi Kokkala, et al. J Med Chem. 2016 Oct 13;59(19):9107-9123.

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IRAP-IN-1 (IRAP inhibitor)

生物&药学活性

物理化学性质&存储条件

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IRAP-IN-1 (IRAP inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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