IRAK inhibitor 1 |CAS:1042224-63-4 Probechem Biochemicals

Chemical Structure : IRAK inhibitor 1

CAS No.: 1042224-63-4

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IRAK inhibitor 1 (IRAK4 inhibitor 1)

货号: PC-43454Not For Human Use, Lab Use Only.

IRAK inhibitor 1 is a potent IRAK4 inhibitor with IC50 of 216 nM, shows little to no activity against JNK-1 and JNK-2 with IC50 of 3.801 uM and >10 uM, respectively.

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5 mg	￥1480	In stock
10 mg	￥2180	In stock
25 mg	￥3780	In stock
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100 mg		Get quote

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生物&药学活性

IRAK inhibitor 1 is a potent IRAK4 inhibitor with IC50 of 216 nM, shows little to no activity against JNK-1 and JNK-2 with IC50 of 3.801 uM and >10 uM, respectively.

物理化学性质&存储条件

分子量	293.37
分子式	C17H19N5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 12.2 mg/mL
Chemical Name/SMILES	2-Pyridinamine, 6-imidazo[1,2-a]pyridin-3-yl-N-4-piperidinyl-

参考文献

1. Buckley GM, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3291-5.

2. Li S, et al. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5567-72.

IRAK inhibitor 1 (IRAK4 inhibitor 1)

生物&药学活性

物理化学性质&存储条件

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IRAK inhibitor 1 (IRAK4 inhibitor 1)

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物理化学性质&存储条件

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