IOX2 | PHD2 inhibitor | Probechem Biochemicals

Chemical Structure : IOX2

CAS No.: 931398-72-0

加入收藏

IOX2 (PHD2 inhibitor, IOX-2)

货号: PC-28710Not For Human Use, Lab Use Only.

IOX2 is a hypoxia-mimicking compound and specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM, promotes articular chondrocyte differentiation, regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2480	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

IOX2 is a hypoxia-mimicking compound and specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM, promotes articular chondrocyte differentiation, regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production.

物理化学性质&存储条件

分子量	352.35
分子式	C19H16N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid

参考文献

1. Sen A, et al. PLoS One. 2013 Nov 11;8(11):e78684.

2. Cheng S, et al. Sci Rep. 2017 Mar 28;7:45408.

3. Deppe J, et al. Arch Toxicol. 2016 May;90(5):1141-50.

IOX2 (PHD2 inhibitor, IOX-2)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

IOX2 (PHD2 inhibitor, IOX-2)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.