INO-1001 |CAS: 501364-82-5 Probechem Biochemicals

Chemical Structure : INO-1001

CAS No.: 501364-82-5

加入收藏

INO-1001 (INO1001;INO 1001)

货号: PC-42837Not For Human Use, Lab Use Only.

INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP).

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥3480	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP).
INO-1001 significantly radiosensitizes human and rodent cell lines at 10 uM (enhancement ratios 1.4-1.6), enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death.
INO-1001 attenuates various aspects of the pathophysiological response in a clinically relevant experimental model of burn/smoke inhalation injury.

物理化学性质&存储条件

分子量	439.53
分子式	C23H25N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-Morpholinopropyl)-5-oxo-6,11-dihydro-5H-indeno[1,2-c]isoquinoline-9-sulfonamide

参考文献

1. Shimoda K, et al. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L240-9.

2. Szabó G, et al. Shock. 2004 May;21(5):426-32.

3. Du X, et al. J Clin Invest. 2003 Oct;112(7):1049-57.

4. Brock WA, et al. Cancer Lett. 2004 Mar 18;205(2):155-60.

INO-1001 (INO1001;INO 1001)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

INO-1001 (INO1001;INO 1001)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.