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IND-114338

Chemical Structure : IND-114338

CAS No.: 1426259-35-9

IND-114338 (IND 114338;IND114338)

货号: PC-60646Not For Human Use, Lab Use Only.

IND-114338 is a novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IND-114338 is a novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.

    物理化学性质&存储条件

    分子量 344.436
    分子式 C20H16N4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(6-methylpyridin-2-yl)-4-(4-(pyridin-3-yl)phenyl)thiazol-2-amine

    参考文献

    1. Giles K, et al. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12.

    2. Li Z, et al. ChemMedChem. 2013 May;8(5):847-57.

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