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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-11β-HSD-INCB13739
INCB13739

Chemical Structure : INCB13739

CAS No.: 872506-67-7

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INCB13739 (INCB-13739;INCB 13739)

货号: PC-35575Not For Human Use, Lab Use Only.

INCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors..

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5 mg ￥2880 In stock
10 mg ￥4580 In stock
25 mg ￥7580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

INCB13739 (INCB-13739) is a potent, selective, oral 11β-HSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.

物理化学性质&存储条件

分子量 398.946
分子式 C19H27ClN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S)-1-[(3-Chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-3-piperidinecarboxamide

参考文献

1. Rosenstock J, et al. Diabetes Care. 2010 Jul;33(7):1516-22.

2. Ge R, et al. Curr Med Chem. 2010;17(5):412-22.

3. Anagnostis P, et al. Metabolism. 2013 Jan;62(1):21-33.

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