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首页-小分子抑制剂&激动剂-Tyrosine Kinase-TAM Receptor (Tyro3-Axl-Mer)-INCB081776
INCB081776

Chemical Structure : INCB081776

CAS No.:

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INCB081776 (INCB 081776)

货号: PC-20332Not For Human Use, Lab Use Only.

INCB081776 is a potent and selective dual inhibitor of AXL and MERTK with IC50 of 16 and 14 nM respectively, 30-fold selectivity over TYRO3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

INCB081776 is a potent and selective dual inhibitor of AXL and MERTK with IC50 of 16 and 14 nM respectively, 30-fold selectivity over TYRO3.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Rios-Doria J, et al. Front Oncol. 2020 Dec 7;10:598477.

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