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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-IN-1233 phosphate
IN-1233 phosphate

Chemical Structure : IN-1233 phosphate

CAS No.: 1093953-38-8

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IN-1233 phosphate (IN1233, IN 1233)

货号: PC-61448Not For Human Use, Lab Use Only.

IN-1233 phosphate is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IN-1233 phosphate is a potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

    物理化学性质&存储条件

    分子量 517.482
    分子式 C26H24N5O5P
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide phosphate

    参考文献

    1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.12120361

    2. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.

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