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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Wee1-IMP7068
IMP7068

Chemical Structure : IMP7068

CAS No.: 2226938-19-6

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IMP7068 (Potrasertib, IMP-7068)

货号: PC-28172Not For Human Use, Lab Use Only.

Potrasertib (MP7068) is a potent and selective WEE1 inhibitor, exhibits superior WEE1/PLK1 selectivity (>435 fold), shows potent cytotoxicity against a wide range of cancer cell lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Potrasertib (MP7068) is a potent and selective WEE1 inhibitor, exhibits superior WEE1/PLK1 selectivity (>435 fold), shows potent cytotoxicity against a wide range of cancer cell lines.

物理化学性质&存储条件

分子量 565.50
分子式 C28H30Cl2N8O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(2,6-dichlorophenyl)-2-((3-methyl-4-((3S,5R)-3,4,5-trimethylpiperazin-1-yl)phenyl)amino)-8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one

参考文献

1. Sui Xiong Cai, et al. Cancer Res (2023) 83 (7_Supplement): 3091.

2. Patent WO2022188802 A1 2022-09-15.

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