IM176OUT05 |CAS: 1643659-96-4 Probechem Biochemicals

Chemical Structure : IM176OUT05

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IM176OUT05

货号: PC-35929Not For Human Use, Lab Use Only.

IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM.

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生物&药学活性

IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM; inhibits mitochondrial OXPHOS and increases lactate production by inducing the expression of glycolysis- and pluripotency-related genes; facilitates the cycle of hair follicle regeneration in mice, stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth.

物理化学性质&存储条件

分子量	255.75
分子式	C11H18ClN5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-1-(2-methyl) phenethyl biguanide hydrochloride

参考文献

1. Son MJ, et al. Exp Mol Med. 2018 Dec 6;50(12):160.

IM176OUT05

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IM176OUT05

生物&药学活性

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