IL-17A PPIm 23 (LP0200 active drug)

Chemical Structure : IL-17A PPIm 23

CAS No.: 2446803-65-0

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货号: PC-47087Not For Human Use, Lab Use Only.

IL-17A PPIm 23 is a potent, orally bioavailable, small-molecule protein-protein interaction modulator (PPIm) of IL-17A, shows potential treatment of psoriasis and other inflammatory diseases.

规格	价格	库存
2 mg	￥3580	In stock
5 mg	￥5580	In stock
10 mg	￥8980	In stock
25 mg		Get quote

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生物&药学活性

IL-17A PPIm 23 (LP0200 active drug) is a potent, orally bioavailable, small-molecule protein-protein interaction modulator (PPIm) of IL-17A, shows potential treatment of psoriasis and other inflammatory diseases.

物理化学性质&存储条件

分子量	474.609
分子式	C27H34N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(1,1-dicyclopropyl-3-((4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl)amino)-3-oxopropan-2-yl)-1-isopropyl-1H-pyrazole-5-carboxamide

参考文献

1. Andrews MD, et al. J Med Chem. 2022 Jun 29. doi: 10.1021/acs.jmedchem.2c00422.