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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-IITR06144
IITR06144

Chemical Structure : IITR06144

CAS No.: 89076-51-7

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IITR06144 (IITR 06144)

货号: PC-38648Not For Human Use, Lab Use Only.

IITR06144 is a novel nitrofuran and exhibits broad-spectrum bactericidal activity against most MDR bacteria (MIC, 0.5 mg/mL).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IITR06144 is a novel nitrofuran and exhibits broad-spectrum bactericidal activity against most MDR bacteria (MIC, 0.5 mg/mL).
    IITR06144 retained its potency against nitrofurantoin-resistant clinical isolates.
    IITR06144 displayed anti-persister, anti-biofilm activity and lack of spontaneous resistance development.
    IITR06144 demonstrated a large therapeutic index with no associated in vitro and in vivo toxicity.

    物理化学性质&存储条件

    分子量 260.205
    分子式 C12H8N2O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-2-nitro-5-(4-nitrostyryl)furan

    参考文献

    1. Timsy Bhando, et al. J Antimicrob Chemother. 2020 Feb 1;75(2):418-428.

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