欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Smoothened (Smo)-IHR-Nac
IHR-Nac

Chemical Structure : IHR-Nac

CAS No.:

加入收藏

IHR-Nac

货号: PC-60379Not For Human Use, Lab Use Only.

A novel cell permeable smoothened antagonist with IC50 of 3.1 nM in Hh-dependent Gli transcriptional activity assay.

规格 价格 库存 数量
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A novel cell permeable smoothened antagonist with IC50 of 3.1 nM in Hh-dependent Gli transcriptional activity assay; blocked Gli2 accumulation at the ciliary tip in response to SAG treatment, also blocks SAG-induced Gpr161 ciliary depletion.

物理化学性质&存储条件

分子量 476.738
分子式 C22H16Cl3N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-acetamido-5-chloro-N-(4-(2,5-dichlorobenzamido)phenyl)benzamide

参考文献

1. Fan CW, et al. Chem Biol. 2014 Dec 18;21(12):1680-9.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: