IHMT-140 (IHMT140)

Chemical Structure : IHMT-140

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货号: PC-27396Not For Human Use, Lab Use Only.

IHMT-140 is a dual-function agent that acts as a DDR1 inhibitor and a methuosis inducer, simultaneously remodels the tumor stromal ECM and activates excessive macropinocytosis, triggers methuosis in pancreatic cancer cells, inhibits tumor invasion and metastasis.

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生物&药学活性

IHMT-140 is a dual-function agent that acts as a DDR1 inhibitor and a methuosis inducer, simultaneously remodels the tumor stromal ECM and activates excessive macropinocytosis, triggers methuosis in pancreatic cancer cells, inhibits tumor invasion and metastasis.

物理化学性质&存储条件

分子量	521.55
分子式	C27H26F3N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Methyl-3-(4-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrazol-1-yl)phenyl)-6-(trifluoromethyl)picolinamide

参考文献

1. Wang B, et al. J Adv Res. 2026 Jul 28:S2090-1232(26)00594-1.

IHMT-140 (IHMT140)

生物&药学活性

物理化学性质&存储条件

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IHMT-140 (IHMT140)

生物&药学活性

物理化学性质&存储条件

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