IGS-1.76 | NCS-1/Ric8a inhibitor | Probechem Biochemicals

Chemical Structure : IGS-1.76

CAS No.: 313480-47-6

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IGS-1.76 (IGS1.76)

货号: PC-35410Not For Human Use, Lab Use Only.

IGS-1.76 is a small molecule inhibitor of human NCS-1/Ric8a interaction with affinity of 1.25 uM (hNCS-1).

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2380	In stock
25 mg	￥3980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

IGS-1.76 is a small molecule inhibitor of human NCS-1/Ric8a interaction with affinity of 1.25 uM (hNCS-1).
IGS-1.76 demonstrates improved binding potency over the phenothiazine FD44, decreasing the abnormally high synapse number and enhancing associative learning in a FXS animal model.

物理化学性质&存储条件

分子量	358.459
分子式	C22H18N2OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(benzo[d]thiazol-2-yl)-3,3-diphenylpropanamide

参考文献

1. Roca C, et al. J Med Chem. 2018 Jul 17. doi: 10.1021/acs.jmedchem.8b00088.

IGS-1.76 (IGS1.76)

生物&药学活性

物理化学性质&存储条件

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IGS-1.76 (IGS1.76)

生物&药学活性

物理化学性质&存储条件

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