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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-IDX17119
IDX17119

Chemical Structure : IDX17119

CAS No.: 1987906-92-2

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IDX17119 (IDX-17119)

货号: PC-62784Not For Human Use, Lab Use Only.

IDX17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IDX17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assays.
    IDX17119 shows activity against broad genotype profile: IC50= 0.0099 uM, 0.2538 uM, 0.1809 uM and 0.0257 uM on genotypes 1b, 2a, 3a and 4a, respectively.

    物理化学性质&存储条件

    分子量 531.513
    分子式 C26H26N7O4P
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-3-(((2,4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid

    参考文献

    1. Pierra Rouvière C, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-41.

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