Chemical Structure : IDRA-21
CAS No.: 22503-72-6
货号: PC-61721Not For Human Use, Lab Use Only.
IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR).
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IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR).
IDRA-21 demonstrates nootropic effects in animal studies, significantly improving learning and memory.
IDRA-21 is 10-30 times more potent than Aniracetam in reversing cognitive deficits induced by alprazolam or scopolamine.
分子量 | 232.687 | |
分子式 | C8H9ClN2O2S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide |
1. Zivkovic I, et al. J Pharmacol Exp Ther. 1995 Jan;272(1):300-9.
2. Thompson DM, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7667-71.
3. Impagnatiello F, et al. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):7053-8.
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