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首页-小分子抑制剂&激动剂-Others-Other Targets-IDE activator Ia1
IDE activator Ia1

Chemical Structure : IDE activator Ia1

CAS No.: 338794-72-2

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IDE activator Ia1 (LDN-1487, IDE activator 1)

货号: PC-26434Not For Human Use, Lab Use Only.

IDE activator Ia1 (IDE activator 1) is a potent, selective activator of insulin degrading enzyme (IDE), activates the hydrolysis of SP1 and FRET1 by IDE to ∼200% and ∼500%, activates the degradation of Aβ by ∼700%.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

IDE activator Ia1 (IDE activator 1) is a potent, selective activator of insulin degrading enzyme (IDE), activates the hydrolysis of SP1 and FRET1 by IDE to ∼200% and ∼500%, activates the degradation of Aβ by ∼700%.

物理化学性质&存储条件

分子量 398.26
分子式 C16H13Cl2N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(4-chlorophenyl)-2,6-dioxocyclohexane-1-carbaldehyde O-((5-chloro-1,2,3-thiadiazol-4-yl)methyl) oxime

参考文献

1. Christelle Cabrol, et al. PLoS One. 2009;4(4):e5274.

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