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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Immune Checkpoints-ICOS inhibitor 9
ICOS inhibitor 9

Chemical Structure : ICOS inhibitor 9

CAS No.: 1006002-58-9

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ICOS inhibitor 9

货号: PC-22944Not For Human Use, Lab Use Only.

ICOS inhibitor 9 is a small molecule inhibitor of ICOS/ICOS-L interaction with IC50 of 29.38 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ICOS inhibitor 9 is a small molecule inhibitor of ICOS/ICOS-L interaction with IC50 of 29.38 uM.
Inducible T cell co-stimulator (ICOS) is a positive immune checkpoint receptor expressed on the surface of activated T cells, which could promote cell function after being stimulated with ICOS ligand (ICOS-L).

物理化学性质&存储条件

分子量 349.21
分子式 C17H14Cl2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((3,4-dichlorobenzyl)oxy)-2-methyl-6-(1H-pyrazol-3-yl)phenol

参考文献

1. Zhang L, et al. bioRxiv [Preprint]. 2024 Aug 7:2024.08.04.606538.

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