ICMT inhibitor C75 | ICMT inhibitor | Probechem Biochemicals

Chemical Structure : ICMT inhibitor C75

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ICMT inhibitor C75 (Isoprenylcysteine carboxylmethyltransferase inhibitor)

货号: PC-49240Not For Human Use, Lab Use Only.

ICMT inhibitor C75 is a potent, specific and cell-permeable inhibitor of the isoprenylcysteine carboxylmethyltransferase (ICMT) with IC50 of 0.5 uM.

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生物&药学活性

ICMT inhibitor C75 is a potent, specific and cell-permeable inhibitor of the isoprenylcysteine carboxylmethyltransferase (ICMT) with IC50 of 0.5 uM.
C75 delays senescence and stimulates proliferation of late-passage HGPS cells and Zmpste24-deficient mouse fibroblasts.

物理化学性质&存储条件

分子量	367.533
分子式	C24H33NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-methoxy-N-(2-(2,2,6,6-tetramethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethyl)aniline

参考文献

1. Judd WR, et al. Journal of Medicinal Chemistry. 2011;54:5031–5047.

ICMT inhibitor C75 (Isoprenylcysteine carboxylmethyltransferase inhibitor)

生物&药学活性

物理化学性质&存储条件

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ICMT inhibitor C75 (Isoprenylcysteine carboxylmethyltransferase inhibitor)

生物&药学活性

物理化学性质&存储条件

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