欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-IAXO-102
IAXO-102

Chemical Structure : IAXO-102

CAS No.: 1115270-63-7

IAXO-102 (IAXO102, IAXO 102)

货号: PC-63208Not For Human Use, Lab Use Only.

IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development.

规格 价格 库存 数量
5 mg ¥1980 In stock
10 mg ¥3280 In stock
25 mg ¥5280 In stock
50 mg Get quote
100 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development.
IAXO-102 inhibits MAPK and p65 NF-kB phosphorylation associated with down regulation of the expression of TLR4 and TLR4 dependent proinflammatory proteins.
IAXO-102 decreases Angiotensin II-induced aortic expansion, rupture and incidence of abdominal aortic aneurysm (AAA).

物理化学性质&存储条件

分子量 585.955
分子式 C35H71NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-a-D-glucopyranoside

参考文献

1. Huggins C, et al. Atherosclerosis. 2015 Oct;242(2):563-70.

2. Kawakita F, et al. Mol Neurobiol. 2017 Oct;54(8):6624-6633.

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: