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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-I1421
I1421

Chemical Structure : I1421

CAS No.: 3054995-92-2

I1421 (I-1421)

货号: PC-22440Not For Human Use, Lab Use Only.

I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM.

物理化学性质&存储条件

分子量 343.36
分子式 C18H18FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-(3-amino-6-(hydroxymethyl)-1H-indazol-1-yl)-3-(4-fluorophenoxy)-2-methylpropan-1-one

参考文献

1. Liu F, et al. Cell. 2024 May 23:S0092-8674(24)00472-0.

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