Chemical Structure : I-OMe-AG-538
CAS No.: 1094048-77-7
货号: PC-72465Not For Human Use, Lab Use Only.
I-OMe-AG-538 (I-OMe-Tyrphostin AG 538) is an ATP-competitive inhibitor of PI5P4Kα with an IC50 of 1 uM, also inhibits the PIP4K2A activity with IC50 of 2.1 uM.
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I-OMe-AG-538 (I-OMe-Tyrphostin AG 538) is an ATP-competitive inhibitor of PI5P4Kα with an IC50 of 1 uM, also inhibits the PIP4K2A activity with IC50 of 2.1 uM.
分子量 | 437.18 | |
分子式 | C17H12INO5 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile |
1. Mindy I Davis, et al. PLoS One. 2013;8(1):e54127.
2. Mayumi Kitagawa, et al. Nat Commun. 2017 Dec 19;8(1):2200.
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