Chemical Structure : I-BET567
CAS No.: 1887237-54-8
货号: PC-72646Not For Human Use, Lab Use Only.
I-BET567 (GSK3383567) is a potent, oral pan-BET inhibitor with Ki of 5-40 nM against BD1/ BD2 of BRD2/3/4/BRDT.
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分子量 | 359.814 | |
分子式 | C17H18ClN5O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(2S,4R)-1-acetyl-4-((5-chloropyrimidin-2-yl)amino)-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxamide |
1. Philip G Humphreys, et al. J Med Chem. 2022 Feb 10;65(3):2262-2287.
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