I-BET432

Chemical Structure : I-BET432

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货号: PC-49467Not For Human Use, Lab Use Only.

I-BET432 is a potent, highly ligand-efficient, orally active pan-BET bromodomain inhibitor with pIC50 of 7.5/7.2 for BRD4 BD1 and BD2 respectively.

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100 mg		Get quote

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生物&药学活性

I-BET432 is a potent, highly ligand-efficient, orally active pan-BET bromodomain inhibitor with pIC50 of 7.5/7.2 for BRD4 BD1 and BD2 respectively.

物理化学性质&存储条件

分子量	327.384
分子式	C18H21N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-7-((R)-1,2-dihydroxyethyl)-1,3-dimethyl-5-(1-methyl-1H-pyrazol-4-yl)-1,3-dihydro-2H-benzo[d]azepin-2-one

参考文献

1. Philip G. Humphreys, et al. J. Med. Chem. 2022.

I-BET432

生物&药学活性

物理化学性质&存储条件

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I-BET432

生物&药学活性

物理化学性质&存储条件

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