I-ABOPX

Chemical Structure : I-ABOPX

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货号: PC-20642Not For Human Use, Lab Use Only.

I-ABOPX is a potent, selective A3 adenosine receptor antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors.

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生物&药学活性

I-ABOPX is a potent, selective A3 adenosine receptor antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors.
I-ABOPX (10 and 40 mg/kg i.v) blocked dose-dependently and surmountable the hypotensive response to APNEA in rats.

物理化学性质&存储条件

分子量	575.36
分子式	C23H22IN5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(3-(4-amino-3-iodobenzyl)-2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetic acid

参考文献

1. Fozard JR, et al. Eur J Pharmacol. 1994 Feb 3;252(2):R5-6.

2. Salvatore CA, et al. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10365-9.

3. Linden J, et al. Mol Pharmacol. 1993 Sep;44(3):524-32.

I-ABOPX

生物&药学活性

物理化学性质&存储条件

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I-ABOPX

生物&药学活性

物理化学性质&存储条件

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