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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-Hyperforin Dicyclohexylammonium Salt
Hyperforin Dicyclohexylammonium Salt

Chemical Structure : Hyperforin Dicyclohexylammonium Salt

CAS No.: 238074-03-8

Hyperforin Dicyclohexylammonium Salt (Hyperforin-DCHA)

货号: PC-21342Not For Human Use, Lab Use Only.

Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms.
Hyperforin possess antidepressant properties through its ability to inhibit the reuptake of serotonin and norepinephrine in neurons.

物理化学性质&存储条件

分子量 718.10
分子式 C35H52O4.C12H23N
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, N-cyclohexylcyclohexanamine (1:1), (1R,5S,6R,7S)-

参考文献

1. Heiser JH, et al. J Neurochem. 2013 Nov;127(3):303-13.

2. Pochwat B, et al. Front Mol Neurosci. 2018 Dec 12;11:456.

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