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首页-小分子抑制剂&激动剂-Others-Other Targets-Hymeglusin
Hymeglusin

Chemical Structure : Hymeglusin

CAS No.: 29066-42-0

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Hymeglusin

货号: PC-22682Not For Human Use, Lab Use Only.

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

物理化学性质&存储条件

分子量 324.42
分子式 C18H28O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-

参考文献

1. Cheng Zhou, et al. Blood Sci. 2024 Jul 10;6(3):e00192.

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