Hydrazinocurcumin |CAS:131068-23-0 Probechem Biochemicals

Chemical Structure : Hydrazinocurcumin

加入收藏

Hydrazinocurcumin

货号: PC-62432Not For Human Use, Lab Use Only.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Hydrazinocurcumin is a synthetic curcumin derivative that inhibits the proliferation of bovine aortic endothelial cells (BAECs) with IC50 of 520 nM without cytotoxicity, inhibits STAT3 phosphorylation and downregulates an array of STAT3 downstream targets.
Hydrazinocurcumin suppresses cell proliferation, depresses cell migration and invasion, induces cell apoptosis.
Hydrazinocurcumin inhibits the cell cycle progression of colon cancer cells via antagonizing of Ca2+/calmodulin functions.

物理化学性质&存储条件

分子量	364.401
分子式	C21H20N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,4'-((1E,1'E)-(1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol)

参考文献

1. Shim JS, et al. Bioorg Med Chem. 2002 Sep;10(9):2987-92.

2. Shim JS, et al. Bioorg Med Chem. 2002 Aug;10(8):2439-44.

3. Wang X, et al. Int J Oncol. 2012 Apr;40(4):1189-95.