Honokiol | SIRT3 activator | Probechem Biochemicals

Chemical Structure : Honokiol

CAS No.: 35354-74-6

加入收藏

Honokiol (NSC 293100)

货号: PC-22371Not For Human Use, Lab Use Only.

规格	价格	库存
10 mg (Free Sample)	￥280	In stock
100 mg	￥980	In stock
250 mg	￥1480	In stock
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Honokiol (NSC 293100) is a natural biphenolic compound derived from the bark of magnolia trees, directly binds to SIRT3 and is an effective activator of deacetylase SIRT3, shows anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties.
Honokiol activates SIRT3 and deacetylates mitochondrial proteins.
Honokiol blocks hypertrophic response of cardiomyocytes in vitro.
Honokiol protects mice from developing cardiac hypertrophy, blocks cardiac hypertrophy of wild-type, but not SIRT3-KO mice.
Honokiol attenuates cardiac fibroblasts proliferation and differentiation into myofibroblasts, reduces ROS production and prevents cardiomyocyte death.
Honokiol activates PGC1α responsive SIRT3 gene promoter leading to increased levels of SIRT3.

物理化学性质&存储条件

分子量	266.34
分子式	C18H18O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5,3'-Diallyl-2,4'-dihydroxybiphenyl

参考文献

1. Pillai VB, et al. Nat Commun. 2015 Apr 14;6:6656.

Honokiol (NSC 293100)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Honokiol (NSC 293100)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.