Chemical Structure : Hinokitiol
CAS No.: 499-44-5
货号: PC-62331Not For Human Use, Lab Use Only.
Hinokitiol (4-Isopropyltropolone, β-Thujaplicin) is a tropolone-related natural compound that can induces apoptosis and cell cycle arrest, exhibits anti-inflammatory and anti-tumor activities, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression.
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Hinokitiol (4-Isopropyltropolone, β-Thujaplicin) is a tropolone-related natural compound that can induces apoptosis and cell cycle arrest, exhibits anti-inflammatory and anti-tumor activities, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression.
Hinokitiol inhibits the proliferation of Chlamydia trachomatis with MIC of 32 ug/mL.
Hinokitiol also can harness such gradients to restore iron transport into, within, and/or out of cells.
| 分子量 | 164.204 | |
| 分子式 | C10H12O2 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one |
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1. Yamano H, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2519-21.
2. Seo JS, et al. BMC Cell Biol. 2017 Feb 27;18(1):14.
3. Grillo AS, et al. Science. 2017 May 12;356(6338):608-616.
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