HhAg1.5 (SAg1.5) | Hedgehog agonist | Probechem Biochemicals

Chemical Structure : HhAg1.5

CAS No.: 612542-14-0

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HhAg1.5 (SAG1.5, Hedgehog Agonist 1.5)

货号: PC-49040Not For Human Use, Lab Use Only.

HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro.

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1 mg	￥1280	In stock
5 mg	￥3280	In stock
10 mg	￥5480	In stock
25 mg		Get quote

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生物&药学活性

HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro.

物理化学性质&存储条件

分子量	526.043
分子式	C28H26ClF2N3OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-1-benzothiophene-2-carboxamide

参考文献

1. Wang C, et al. Nat Commun. 2014 Jul 10;5:4355.

2. Liu J, et al. Onco Targets Ther. 2020 Nov 19;13:11957-11973.

3. Abhisek Mitra, et al. Transl Res. 2019 Mar;205:44-50.

4. Frank-Kamenetsky M, et al. J Biol. 2002;1:10.

HhAg1.5 (SAG1.5, Hedgehog Agonist 1.5)

生物&药学活性

物理化学性质&存储条件

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HhAg1.5 (SAG1.5, Hedgehog Agonist 1.5)

生物&药学活性

物理化学性质&存储条件

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