Hexamethylene bisacetamide |CAS:3073-59-4 Probechem Biochemicals

Chemical Structure : Hexamethylene bisacetamide

CAS No.: 3073-59-4

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Hexamethylene bisacetamide (HMBA;NSC 95580)

货号: PC-61330Not For Human Use, Lab Use Only.

Hexamethylene bisacetamide (HMBA, NSC 95580) is a cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.

规格	价格	库存
50 mg	￥880	In stock
100 mg	￥1280	In stock
200 mg	￥1980	In stock
1 g		Get quote

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生物&药学活性

Hexamethylene bisacetamide (HMBA, NSC 95580) is a cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.
Hexamethylene bisacetamide causes MEL cell differentiation by acting as a selective BD2 (bromodomain 2) inhibitor, kills Myc-induced lymphoma cells in vitro and in vivo.
Hexamethylene bisacetamide also is a small molecule inducer of HEXIM1 expression, inhibits the metastasis of breast cancer to lung in PyMT mice.

物理化学性质&存储条件

分子量	200.28
分子式	C10H20N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,6-Hexanebisacetamide

参考文献

1. Ketchart W, et al. Oncogene. 2013 Aug 15;32(33):3829-39.

2. Nilsson LM, et al. Cancer Res. 2016 Apr 15;76(8):2376-83.

3. Dey A, et al. Cell Cycle. 2008 Dec;7(23):3759-67.

Hexamethylene bisacetamide (HMBA;NSC 95580)

生物&药学活性

物理化学性质&存储条件

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Hexamethylene bisacetamide (HMBA;NSC 95580)

生物&药学活性

物理化学性质&存储条件

参考文献

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