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首页-小分子抑制剂&激动剂-Others-Other Targets-Heparanase-IN-2
Heparanase-IN-2

Chemical Structure : Heparanase-IN-2

CAS No.: 340183-01-9

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Heparanase-IN-2

货号: PC-73272Not For Human Use, Lab Use Only.

Heparanase-IN-2 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.12 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Heparanase-IN-2 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.12 uM.
    Heparanase-IN-2 decreases the mRNA levels of genes encoding for proangiogenic factors, such as FGF1/2, VEGF, and MMP-9.

    物理化学性质&存储条件

    分子量 763.496
    分子式 C38H20Cl2N4O10
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2,2'-((isophthaloylbis(azanediyl))bis(3-chloro-4,1-phenylene))bis(1,3-dioxoisoindoline-5-carboxylic acid)

    参考文献

    1. Daniele Pala, et al. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1685-1696.

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