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首页-小分子抑制剂&激动剂-Autophagy-Hemin
Hemin

Chemical Structure : Hemin

CAS No.: 16009-13-5

Hemin (Hemin chloride)

货号: PC-45633Not For Human Use, Lab Use Only.

Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
Hemin increases the size of autophagic vacuoles and induces mitophagy in K562 cells; a heme oxygenase (HO)‑1 inducer.

物理化学性质&存储条件

分子量 651.9403
分子式 C34H32ClFeN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 6.6 mg/mL

Chemical Name/SMILES

Ferrate(2-), chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-5-13)-

参考文献

1. Fader CM, et al. Biol Cell. 2016 Apr;108(4):77-95.

2. Higdon AN, et al. Am J Physiol Heart Circ Physiol. 2012 Apr 1;302(7):H1394-409.

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