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Hedgehog-IN-7d

Chemical Structure : Hedgehog-IN-7d

CAS No.: 330796-24-2

Hedgehog-IN-7d (Gli inhibitor 7d)

货号: PC-62175Not For Human Use, Lab Use Only.

Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM.

    物理化学性质&存储条件

    分子量 490.8
    分子式 C23H15ClF4N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-urea

    参考文献

    1. Brunton SA, et al. J Med Chem. 2008 Mar 13;51(5):1108-10.

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