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首页-小分子抑制剂&激动剂-Others-Other Targets-HTS13286
HTS13286

Chemical Structure : HTS13286

CAS No.: 727359-12-8

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HTS13286 (HTS 13286)

货号: PC-20302Not For Human Use, Lab Use Only.

HTS13286 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    HTS13286 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).
    HTS13286 shows little to no activity against AQP3, AQP7, and AQP8.

    物理化学性质&存储条件

    分子量 415.51
    分子式 C16H13N7OS3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-((4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(5-(thiophen-2-yl)-1,3,4-thiadiazol-2-yl)acetamide

    参考文献

    1. Sabina Jelen, et al. J Biol Chem. 2011 Dec 30;286(52):44319-25.

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